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A new lignan from the flowers of Hibiscus sabdariffa L. (Malvaceae)

Journal: Natural Product Research
Author: Huu Phuc Dang
Link: https://www.tandfonline.com/doi/abs/10.1080/14786419.2019.1667354
Abstract

From MeOH-soluble fraction of the flowers of Hibiscus sabdariffa (Malvaceae), one new lignan, (+)-4-O-methyl-5′-methoxy-secoisolariciresinol (1), together with four known compounds (2–5) were isolated. The structures were elucidated based on NMR spectroscopic analysis. The absolute configuration of 1 was determined based on the Cotton effects in the CD spectrum. Compounds 1, 3 and 4 showed antioxidant activities with the SC50 values of 56.9, 19.3 and 22.7 µM, respectively.